This week on Sci­ence for the Peo­ple, we are talk­ing about a con­tro­ver­sial the­o­ry in evo­lu­tion­ary biol­o­gy that has led to research on the role of sin­gle muta­tions that dras­ti­cal­ly alter the body plan of organ­isms. Guest host Ani­ka Hazra speaks with Olivi­er Riep­pel, cura­tor of Evo­lu­tion­ary Biol­o­gy at the Field Muse­um, about the his­to­ry of this the­o­ry and where it stands with­in mod­ern sci­ence. And she talks with Nipam Patel, pro­fes­sor of Mol­e­c­u­lar Cell Biol­o­gy and Inter­gra­tive Biol­o­gy at UC Berke­ly, about his exper­i­men­tal research on the role of cer­tain mutat­ed genes in the phys­i­cal devel­op­ment of crustaceans.